Mensys Online Shop
| Category: | General - Books | By: | O'Reilly |
| More info: | www.oreilly.com ... | Author(s): | Ian Korf, Mark Yandell, Joseph Bedell |
| Pages: | 339 | Year of publication: | 2003 |
| Sequence similarity is a powerful tool for discovering biological function. Today we can use comparative sequence analysis to understand genomes. BLAST (Basic Local Alignment Search Tool), is a sophisticated software package for rapid searching of nucleotide and protein databases. It is one of the most important software packages used in sequence analysis and bioinformatics. Most users of BLAST, however, seldom move beyond the program's default parameters. BLAST is the only book completely » Read more... |  |
All prices are in Euro excl. VAT (19%, for books 6%) and excl. shipping.
E-mail or call us at +31 (0)23 548 20 20 for licences, upgrades and other questions.
Sequence similarity is a powerful tool for discovering biological function. Today we can use comparative sequence analysis to understand genomes. BLAST (Basic Local Alignment Search Tool), is a sophisticated software package for rapid searching of nucleotide and protein databases. It is one of the most important software packages used in sequence analysis and bioinformatics. Most users of BLAST, however, seldom move beyond the program's default parameters. BLAST is the only book completely devoted to this suite of tools. It offers biologists, computational biology students, and bioinformatics professionals a clear understanding of BLAST as well as the science it supports. This book shows you how to move beyond the default parameters, get specific answers using BLAST, and how to interpret your results. The book also contains tutorial and reference sections covering NCBI-BLAST and WU-BLAST, background material to help you understand the statistics behind BLAST, Perl scripts to help you prepare your data and analyze your results, and tips and tricks for configuring BLAST to meet your own research needs. Some of the topics covered include: BLAST basics and the NCBI web interface; How to select appropriate search parameters; BLAST programs: BLASTN, BLASTP, BLASTX, TBLASTN, TBLASTX, PHI-BLAST, and PSI BLAST; Detailed BLAST references, including NCBI-BLAST and WU-BLAST; Understanding biological sequences; Sequence similarity, homology, scoring matrices, scores, and evolution; Sequence Alignment; Calculating BLAST statistics; Industrial-strength BLAST, including developing applications with Perl and BLAST.